ADVERTISEMENT: Radiopaedia is free thanks to our supporters and advertisers. Cystic adrenal neuroblastoma with liver metastasis is a rare condition. Neuroblastoma rarely presents as a cystic suprarenal mass that is difficult to differentiate from adrenal hemorrhage, … AJR Am J Roentgenol 1986;146(1):113–117. Cystic neuroblastoma in infants: radiographic and pathologic features. Cassady C, Winters WD (1997) Bilateral cystic neuroblastoma: imaging features and differential diagnoses. There are two methods of neuroblastoma staging, one that is based on post-operative patients (INSS) and one developed for pre-treatment patients (INRGSS). Wilms tumors are the most common pediatric renal mass, accounting for over 85% of cases 1,8 and accounts for 6% of all childhood cancers 2. Approximately 80% of these tumors are found before the age of 5 years. Neuroblastoma is a malignancy derived from primitive neural crest cells that would normally form the sympathetic nervous system. Cystic adrenal neuroblastoma with liver metastasis is a rare condition. Differential diagnosis in adrenal masses includes hamartoma and hemorrhage. Doppler-US imaging revealed internal vascularisation. Cystic formation in association with adrenal neuroblastoma may be related to hemorrhage and necrosis of the tumor. Neuroblastoma, a relatively common tumor in infants, is rarely present at birth. US of the left upper quadrant shows a complex multiloculated mass (arrow) with thin septations, internal echoes and some calcifications in superior and medial location to the left kidney (asterix). There were 22 patients (54%) in the group without cystic changes and 19 patients (46%) in the group with cystic changes. Neuroblastoma is the most common perinatal malignancy, and the adrenal gland is the most common site of origin [1, 2]. Axial unenhanced CT of the abdomen shows thin wall of the left cystic mass and calcification. Chen CP, Chen SH, Chuang CY, Lee HC, Hwu YM, Chang PY, Chen ML, Chen BF (1997) Clinical and perinatal sonographic features of congenital adrenal cystic neuroblastoma: a case report with review of the literature. A solid mass is the typical appearance of this neoplasm, while cystic formation is uncommon. The content of cysts is usually haemorrhagic, although it may be serous or gelatinous [2, 5]. Deeg KH, Bettendorf U, Hofmann V. Differential diagnosis of neonatal adrenal haemorrhage and congenital neuroblastoma by colour coded Doppler sonography and power Doppler sonography. Eo H(1), Kim JH, Jang KM, Yoo SY, Lim GY, Kim MJ, Kim OH. cystic congenital adrenal neuroblastoma were reviewed to compare the additional diagnostic value of CT and MRI when paired with ultrasound. MRI demonstrates a cystic lesion in the right adrenal gland. Br J Radiol Nov;71(851):1205-7 (PMID: 10434918),  Differential diagnosis in adrenal … Korean journal of radiology. We present an unusual case of congenital cystic fetal neuroblastoma of the right adrenal gland detected at 37 weeks' gestation which evolved into a complex echogenic mass 6 weeks after birth. On Doppler-US blood flow was seen in the cyst. Radiographics Jul-Aug;19(4):949-63 (PMID: 10464802). Laparotomy and left adrenalectomy confirmed the diagnosis of a cystic neuroblastoma. The patient is developing normally at 1 year of age. ADVERTISEMENT: Supporters see fewer/no ads. We present a report of three patients of cystic neuroblastoma who aged 23 days, one year and 3 months respectively. No solid components were detected in the lesion. Atkinson GO Jr, Zaatari GS, Lorenzo RL, Gay BB Jr, Garvin AJ (1986) Cystic neuroblastoma in infants: radiographic and pathologic features. Purely cystic neuroblatomas are often discovered prenatally. MRI revealed that the lesion was cystic in nature with the thick walls of the lesion showing contrast-enhancement. The imaging findings for cystic congenital adrenal neuroblastoma were reviewed to compare the additional diagnostic value of CT and MRI when paired with ultrasound. 12 (1): 52-8. Lee SY, Chuang JH, Huang CB, Hsiao CC, Wan YL, Ng SH, Lee TY, Ko SF (1998) Congenital bilateral cystic neuroblastoma with liver metastases and massive intracystic haemorrhage. Neuroblastoma is the most common malignant tumour in infancy originating in about 70% of cases in the adrenal gland [1, 2]. Eo H, Kim JH, Jang KM, Yoo SY, Lim GY, Kim MJ, Kim OH. Cystic neuroblastoma identified by prenatal ultrasonography. 3. It presents in two forms: solid (56%) and cystic (44%). We present an 11-month-old girl with predominantly cystic bilateral neuroblastomas and distant lymph-node metastasis. Axial spin-echo fat-saturated T1-weighted MRI of the cystic tumour shows high signal intensity. Fistulous communication between an adrenal cystic neuroblastoma and the large bowel has never to our knowledge been reported before. The content of cysts is usually haemorrhagic, although it may be serous or gelatinous [2, 5].